Process for preparing benzyl-substituted rhodanine derivatives

Details Process for preparing benzyl-substituted rhodanine derivatives Process for preparing benzyl-substituted rhodanine derivatives

1994-12-21

1996-10-08

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548186, 548189, C07D27704

Patent

active

055632777

ABSTRACT:
The instant invention provides a novel process for preparing benzyl-substituted rhodanine derivatives. The process is particularly useful for synthesizing the enantiomers of such derivatives. Also provided are novel benzyl-substituted mercaptopropanoic acids and benzyl-substituted thiazolidinones. Such compounds are useful for treating inflammatory bowel disease and, accordingly, the present invention provides a method of treating inflammatory bowel disease in mammals utilizing such novel compounds as well as pharmaceutical compositions containing same.

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