Process for preparing AZT (3'-azido-3'-deoxy-thymidine) and rela

Details Process for preparing AZT (3'-azido-3'-deoxy-thymidine) and rela Process for preparing AZT (3'-azido-3'-deoxy-thymidine) and rela

1990-10-25

1992-06-23

Shen, Cecilia

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 1700

Patent

active

051244420

ABSTRACT:
The present invention relates to a process for preparing a compound of formula I ##STR1## from a compound of formula II ##STR2## via a compound of formula IV ##STR3## and to a compound of formula IV by way of an intermediate in the preparation of a compound of formula I.

REFERENCES:
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Hayauchi et al., CA 109-211404s (1988).
Yamamoto et al., J. C. S. Perkin I, p. 306 (1980).
Glinski et al., Journal of Organic Chemistry, 38, 4299 (1973).
Colla et al., European Journal Med. Chem.-Chim. Ther., 20, 295 (1985).
Lin et al., Journal of Medicinal Chemistry, 26, 544 (1983).
Loibner et al., Justus Liebigs Annalen Der Chemie, 78 (1978).
Kimura et al., Bulletin of the Chemical Society of Japan, 52, 1191 (1979).
Chemical Abstracts, No. 12166X, vol. 88, 590 (1978).

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