Process for preparing antihistamine tannates

Details Process for preparing antihistamine tannates Process for preparing antihistamine tannates

1996-06-28

1997-09-02

Nazario-Gonzalez, Porfirio

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C 6988

Patent

active

056634153

ABSTRACT:
A process for preparing pure antihistamine tannate compositions. The antihistamine in the form of its free base is contacted with tannic acid in the presence of water for a period of time of about 5 minutes to 4 hours and at a maximum temperature such that not more than about 5 wt. % of the antihistamine tannate will be decomposed. Water is removed from the antihistamine tannate by freeze-drying.

REFERENCES:
patent: 5599846 (1997-02-01), Chopdekar

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