Process for preparing antibiotics D788-7

Details Process for preparing antibiotics D788-7 Process for preparing antibiotics D788-7

1989-08-21

1990-09-04

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

20415764, 20415782, 424116, 424120, 424122, 435170, 435173, 43525235, 435886, 514 34, 536 64, 536 184, 552201, C12P 1956, C07H 1524

Patent

active

049544381

ABSTRACT:
This invention relates to a process for preparing an antibiotic D788-7 wherein, after culturing carborubicin-producing bacteria, the obtained culture liquid is extracted in acidic conditions while stirring to be absorbed to synthetic resin, followed by desorption from the resin and elution with acetone and the resulting acetone solution containing carborubicin is converted into an antibiotic D788-7 by photo radiation, for obtaining D788-7 in the purified form from the reaction solution. The production yield for D788-7 is extremely high and its use as an antitumor agent can be made possible.

REFERENCES:
patent: 4612371 (1986-09-01), Yoshimoto et al.

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