Process for preparing anhydrous Aripirazole type I

Details Process for preparing anhydrous Aripirazole type I Process for preparing anhydrous Aripirazole type I

2007-10-24

2011-10-18

Bernhardt, Emily (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S253070

Reexamination Certificate

active

08039621

ABSTRACT:
Type I anhydrous aripiprazole is prepared by dissolving aripiprazole (or an acid salt thereof) in an alcoholic solvent, optionally containing water, at elevated temperature, adding seed crystals of Type 1 anhydrous aripiprazole to the solution, cooling the mixture, and isolating crystals aripiprazole and drying the isolated crystals to obtain low moisture Type 1 anhydrous aripiprazole.

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