Process for preparing androst-4-ene-3,17-dione

Details Process for preparing androst-4-ene-3,17-dione Process for preparing androst-4-ene-3,17-dione

1977-10-09

1981-10-06

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

435172, 435865, C12P 3316

Patent

active

042936446

ABSTRACT:
Mutant which is used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to yield predominantly androst-4-ene-3,17-dione (AD) and small amounts of androsta-1,4-diene-3,17-dione (ADD). AD is a valuable intermediate to make useful steroids.

REFERENCES:
patent: 2602769 (1952-07-01), Murray et al.
patent: 3388042 (1968-06-01), Arima et al.
patent: 3507749 (1970-04-01), Sih
patent: 3684657 (1972-08-01), Kraychy et al.
patent: 3759791 (1973-09-01), Marsheck et al.
patent: 4035236 (1977-07-01), Wovcha
Mamoli et al., Ber. 70, 470 & 2079 (1937).

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