Process for preparing and using guanidine derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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548952, 548546, 546243, 540356, 540526, C07D21144, C07D20712, C07D20504, C07D22310

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active

056962568

ABSTRACT:
##STR1## wherein R is a substituted or unsubstituted hydrocarbon residue or acyl group; X is an electron withdrawing group; Y.sup.1 and Y.sup.2, which are the same or different, are each independently oxygen or sulfur; and A is a substituted or unsubstituted, divalent hydrocarbon residue have potent reactivity, this being useful in preparing guanidine derivatives.

REFERENCES:
patent: 4287346 (1981-09-01), Tanaka et al.
patent: 4742060 (1988-05-01), Shiokawa et al.
patent: 4845106 (1989-07-01), Shiokawa et al.
Chemical Abstracts, vol. 89(17):146820b (1978).
Chupp et al., J. Org. Chem., 43(18), 3553-59, 1978.
G.J. Durant et al., "Cyanoguanidine--Thiourea Equivalence in the Development of the Histamine H2-Receptor Antagonist, Cimetidine," Journal of Medicinal Chemistry, vol. 20, No. 7, (1977), pp. 901-906.

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