Process for preparing an intermediate for CNS depressants

Details Process for preparing an intermediate for CNS depressants Process for preparing an intermediate for CNS depressants

1976-07-27

1977-11-22

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260289C, C07D21710

Patent

active

040595854

ABSTRACT:
Disclosed is a process for preparing (4a,13b-trans)-1,2,4,4a,8,9,13b,14-octahydro-3H-benzo[6,7]cyclohepta[1,2,3 -de]-pyrido[2,1-a]isoquinolin-3-one involving a 1,3-cycloaddition of a 4-halo-1-butene to 1,7,8,12b-tetrahydrobenzo[1,2]cyclohepta-[3,4,5-de]isoquinoline N-oxide.

REFERENCES:
patent: 3657250 (1972-04-01), Bruderlein et al.

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