Process for preparing an intermediate

Details Process for preparing an intermediate Process for preparing an intermediate

1989-12-20

1991-06-11

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562401, C07C 6976

Patent

active

050233653

ABSTRACT:
A process is described for preparing an intermediate in the synthesis of naproxen.
The intermediate, namely the methyl ester of S(+)-2-(5-bromo-6-methoxy-2-naphthyl)-propionic acid or of its 5-chloro analogue, is prepared by preferential crystallization from mixtures with its enantiomer.

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