Process for preparing an imidazole derivative

Details Process for preparing an imidazole derivative Process for preparing an imidazole derivative

1981-04-03

1983-04-26

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23364

Patent

active

043813950

ABSTRACT:
This invention relates to new processes for preparing an imidazole derivative, i.e. cimetidine, by (1) reacting an imidazolylmethylthioethylamine with an amidine or (2) reacting a N-cyano-N'-imidazolylmethylthioethyl formamidine with methylamine or (3) reacting a N-methyl-N'-imidazolylmethylthioethyl formamidine with cyanamide.

REFERENCES:
patent: 3950333 (1976-04-01), Durant et al.
patent: 4128658 (1978-12-01), Price et al.
March, J., Advanced Organic Chemistry, McGraw Hill, New York, 1968, p. 294.
Derwent Abstract 18809X (Belgian 832,665).
Derwent Abstract 09733D (WP 8100109).

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