Process for preparing an enantiomer of a carbazole derivative

Details Process for preparing an enantiomer of a carbazole derivative Process for preparing an enantiomer of a carbazole derivative

1995-05-26

1997-04-08

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20988

Patent

active

056189486

ABSTRACT:
A (+) or (-) enantiomer of a compound of formula (I) wherein R.sup.4 is methyl or ethyl, or a salt, solvate or hydrate thereof, processes for preparing said compounds and pharmaceutical compositions containing them. Compounds of formula (+) are 5-HT.sub.1 -like agonists. ##STR1##

REFERENCES:
patent: 4257952 (1981-03-01), Mooradian
Hacksell et al., "Chirality in drug research and design", Trends in Biotechnology, vol. 11, pp. 73-74 (1993).
Ariens, "Nonchiral homochiral and composite chiral drugs", Trends in Pharmacological Sciences, vol. 14, pp. 68-75 (1993).

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