Process for preparing aminobenzoate esters

Details Process for preparing aminobenzoate esters Process for preparing aminobenzoate esters

2007-07-27

2009-06-16

Zucker, Paul A (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

Reexamination Certificate

active

07547798

ABSTRACT:
The present invention herein provides a process for making an aminobenzoate ester of an alcoholic organic compound. In one aspect, there is provided a process for making an aminobenzoate ester comprising the steps of: (a) providing a reaction mixture comprising an alkyl aminobenzoate, an alcohol reagent and a suitable transesterification catalyst; (b) introducing an auxiliary alcohol to the reaction mixture; and (c) exposing the reaction mixture to conditions effective to provide an end-product mixture comprising the aminobenzoate ester.

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M.G. Abdullaev, Development of the Method of Novocain Production, Pharma. Chem. Jour., vol. 35, No. 10, 2001, pp. 556-559.

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