Process for preparing .alpha.-L-aspartyl-L-phenylalanine methyl

Details Process for preparing .alpha.-L-aspartyl-L-phenylalanine methyl Process for preparing .alpha.-L-aspartyl-L-phenylalanine methyl

1984-10-16

1986-09-23

Phillips, Delbert R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07K 506

Patent

active

046134603

ABSTRACT:
A process for preparing .alpha.-L-aspartyl-L-phenylalanine methyl ester: ##STR1## in which: (a) the compound methyl N(.alpha.-L-aspartyl).alpha.-aminocinnamate, protected at the nitrogen, of formula: ##STR2## where R is a protector group at the nitrogen, is subjected to hydrogenation at the olefin bond by means of gaseous hydrogen in the presence of a hydrogenation catalyst, to give the compound of formula: ##STR3## where R has the aforesaid meaning, in the form of a mixture of .alpha.-L-aspartyl-L-phenylalanine methyl ester protected at the nitrogen, and .alpha.-L-aspartyl-D-phenylalanine methyl ester protected at the nitrogen;

REFERENCES:
patent: 3901871 (1975-08-01), Anderson
King et al., J. Org. Chem., 46, 4780-4782 (1981).
Vogel, Practical Organic Chem., 3rd Ed., Langmans, Green and Co., N.Y., p. 474.

Affiliated with

Also associated with

Rating

Process for preparing .alpha.-L-aspartyl-L-phenylalanine methyl does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing .alpha.-L-aspartyl-L-phenylalanine methyl , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing .alpha.-L-aspartyl-L-phenylalanine methyl will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-765423