Process for preparing alkali salts of cephalosporin C

Details Process for preparing alkali salts of cephalosporin C Process for preparing alkali salts of cephalosporin C

1993-09-27

1995-04-04

Rizzo, Nicholas

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540228, C07D50128

Patent

active

054039290

ABSTRACT:
Zinc salts of Cephalosporin C are dissolved in a solution of halides of univalent metals at a temperature of 0.degree.-25.degree. C. and the pH is adjusted to 1-2 prior to being ion exchanged with a sodium form cation-exchange resin packed in a column and being eluted with a water miscible solvent. The column can be further eluted with a solution of halides of univalent metals.

REFERENCES:
patent: 3661901 (1972-05-01), Bickel et al.

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