Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1995-05-26
1997-07-15
Dees, Jose G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C07C23102
Patent
active
056485352
ABSTRACT:
A process for the production of N-acylaminophenols by the concurrent hydrogenation of a nitrophenol to an aminophenol and the acylation of the aminophenol with acyl anhydride takes place on a continuous basis in a stirred tank reactor in which liquid product is continuously withdrawn from the reactor. Of particular interest is the manufacture of acetaminophen, N-acetyl-p-aminophenol by continuous reaction of p-ntirophenol, hydrogen and acetic anhydride.
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Ullmann's Encyclopedia of Industrial Chemistry, vol. A13, 1989, "Hydrogenation and Dehydrogenation".
CA(77): 126261u (1972) --Koengetal -"Catalytic Manufacture of p-acetamidophenol"--DE 1493727.
Derwent Abstract --Acc. #C66-F38223--"Production of Para-Acetamido-Phenol From Para-Nitrophenol"--DE 1493727.
Foster James A.
Mueller Werner H.
Ryan Debra A.
Wiezer Hartmut
Cebulak Mary C.
Dees Jos,e G.
Hoechst Celanese Corp.
McGinnis James L.
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