Process for preparing acemetacin

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20928

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active

046007830

ABSTRACT:
Acemetacin is prepared by reaction of an indometacin with tert.-butyl halogenoacetate and subsequent cleavage with sulphuric acid and/or sulphonic acid.

REFERENCES:
patent: 4104278 (1978-08-01), Boltze et al.
patent: 4165428 (1979-08-01), Noda et al.

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