Process for preparing a sterile high molecular weight...

Details Process for preparing a sterile high molecular weight... Process for preparing a sterile high molecular weight...

2011-05-10

2011-05-10

Peselev, Elli (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S055100

Reexamination Certificate

active

07939655

ABSTRACT:
A process for preparing a sterile ready-to-use aqueous pharmaceutical formulation comprises a high molecular weight hyaluronic acid salt (HA) at a specified concentration, comprising the steps of: providing an aqueous formulation comprising high molecular weight HA at a concentration of less than the specified final concentration; passing said aqueous formulation through a filter having a pore sizeless than 0.45 pm; concentrating said aqueous formulation by applying a vacuum and boiling off water until said specified concentration is reached.

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XP-002262433, Feb. 16, 1990, Showa Sangyo Co.

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