Process for preparing a solid encapsulated medicament

Details Process for preparing a solid encapsulated medicament Process for preparing a solid encapsulated medicament

1990-06-26

1992-02-04

Spruill, Robert L.

Package making

Methods

With contents treating

53440, 53471, 53900, 424454, B65B 728, B65B 6308, A61K 964

Patent

active

050850334

ABSTRACT:
The present invention relates to the preparation of encapsulated products containing a solid dosage form prepared with up to 35% of an edible matrix material. The composition may be introduced into the capsule as a powder and the capsule containing the powder mixture may then be heated to melt the matrix. The resulting capsule products exhibit the favorable texture of a capsule in conjunction with the hardness, shelf stability and security of the solid formulation. The composition of the present invention may be prepared and used as a direct tableting granulation as well as the filler or core for the capsule product. A method and corresponding apparatus are likewise disclosed and contemplated herein.

REFERENCES:
patent: 3432592 (1969-03-01), Speiser
patent: 4028024 (1977-06-01), Moreland
patent: 4163354 (1979-08-01), Austin
patent: 4497157 (1985-02-01), Durr et al.
patent: 4591475 (1986-05-01), Tomka et al.
patent: 4655840 (1987-04-01), Wittwer et al.
patent: 4673438 (1987-06-01), Wittwer et al.
patent: 4734149 (1988-03-01), Brown
patent: 4928840 (1990-05-01), Barshay et al.
patent: 4936074 (1990-06-01), Graham

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