Process for preparing a porous graft containing endothelial cell

Details Process for preparing a porous graft containing endothelial cell Process for preparing a porous graft containing endothelial cell

1993-05-04

1997-06-03

Willse, David H.

Surgery

Blood vessel or graft preparation

623 1, A61F 202, A61F 206

Patent

active

056348797

ABSTRACT:
A process for the production of prostheses wherein endogenic tissue material is substantially mechanically comminuted and, if necessary, additionally enzymatically digested to tissue particles, whose sizes fall within very narrow limits. A preshaped carrier material is treated with the resultant suspension. In the case of a porous carrier material the suspension is filtered through the material, whereas with less or non-porous carrier material the suspension is applied to the material surface by centrifuging. Unlike the case of corresponding prior art processes, as a result of this improvement, the process according to the invention can be performed very rapidly, i.e., directly during the operation and in a closed system.

REFERENCES:
patent: 5035708 (1991-07-01), Alchas et al.
patent: 5171261 (1992-12-01), Noishiki et al.
patent: 5230693 (1993-07-01), Williams et al.

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