Process for preparing a controlled release composition

Details Process for preparing a controlled release composition Process for preparing a controlled release composition

1998-07-07

2000-08-15

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424451, 424452, 424465, 424474, 424475, 424484, 424486, 424487, 424469, 424470, 424464, 424457, 5147723, 514784, 514785, 514786, 514787, A61K 928, A61K 948, A61K 922, A61K 952

Patent

active

061032646

ABSTRACT:
A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which comprises granulating the active ingredient with a molten matrix material or with a matrix material while it is being melted and with optional additional inactive materials at a first elevated temperature, then cooling and screening the granulate, forming a fluidized bed of the resulting material at a second elevated temperature, and recovering the resulting product; and the product formed by the process.

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