Process for preparing 9.alpha.-OH BN acid methyl ester

Details Process for preparing 9.alpha.-OH BN acid methyl ester Process for preparing 9.alpha.-OH BN acid methyl ester

1979-04-23

1980-07-22

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

435 58, C12P 3316

Patent

active

042140510

ABSTRACT:
Valuable steroid intermediates, 9.alpha.-hydroxyandrost-4-ene-17.beta.-ol-3-one (9.alpha.-OH testosterone), 9.alpha.-hydroxy-3-ketobisnorchol-4-en-22-ol (9.alpha.-OH BN alcohol) and 9.alpha.-hydroxy-3-ketobisnorchol-4-en-22-oic methyl ester (9.alpha.-OH BN acid methyl ester), prepared by microbiological conversion of steroids having 17-alkyl side chains of 8 to 10 carbons.

REFERENCES:
patent: 4029549 (1977-06-01), Antosz et al.
patent: 4032408 (1977-06-01), Jiu et al.
patent: 4035236 (1977-07-01), Wovcha

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