Process for preparing 6-(substituted phenyl)-4,5-dihydro-3(2H)-p

Details Process for preparing 6-(substituted phenyl)-4,5-dihydro-3(2H)-p Process for preparing 6-(substituted phenyl)-4,5-dihydro-3(2H)-p

1984-03-28

1985-06-11

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544239, C07D23704, A61K 3150

Patent

active

045230110

ABSTRACT:
6-(Substituted phenyl)-4,5-dihydro-3(2H)-pyridazinone compounds possessing strong platelet aggregation inhibiting activity and blood pressure depressing activity, having the general formula: ##STR1## wherein R.sup.1 is hydrogen or lower alkyl; R.sup.2 is hydrogen, lower alkyl, lower alkylthio or the grouping R.sup.5 --NH-- where R.sup.5 is lower alkyl; R.sup.3 is phenyl, pyridyl, benzyl, lower alkyl or a substituted phenyl group carrying at any desired position on the benzene ring thereof the grouping: ##STR2## where R.sup.1 has the same meaning as given above; R.sup.4 is hydrogen or halogen; n is 0 or 1; and when both R.sup.2 and R.sup.3 are lower alkyl groups, R.sup.2 and R.sup.3 may be combined together with the bridging member ##STR3## between them to form the structure: ##STR4## where m is 2 or 3, as well as physiologically acceptable acid-addition salts thereof, and processes for preparing them.

REFERENCES:
patent: 3845050 (1974-10-01), Lebkuecher et al.
patent: 3947437 (1976-03-01), Johnston

Affiliated with

Also associated with

Rating

Process for preparing 6-(substituted phenyl)-4,5-dihydro-3(2H)-p does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing 6-(substituted phenyl)-4,5-dihydro-3(2H)-p, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing 6-(substituted phenyl)-4,5-dihydro-3(2H)-p will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1184121