Process for preparing 6-O-alkyl-9-oxime erythromycin B

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 74, 514 29, C07H 504, C07H 1708, A61K 3171

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active

059327103

ABSTRACT:
A process of preparing a 6-O-alkyl derivative of 9-oxime erythromycin B is provided. Intermediates used in the preparation of a 6-O-alkyl 9-oxime erythromycin B are also provided. Pharmaceutical compositions containing a 6-O-alkyl derivative of 9-oxime erythromycin B and the use of those compositions to treat bacterial infections are also provided.

REFERENCES:
patent: 4496717 (1985-01-01), Adachi et al.
patent: 4670549 (1987-06-01), Morimoto et al.
patent: 4672109 (1987-06-01), Watanabe et al.
patent: 5141926 (1992-08-01), Weber et al.

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