Process for preparing 6-aminopenicillanic acid

Details Process for preparing 6-aminopenicillanic acid Process for preparing 6-aminopenicillanic acid

1976-11-26

1978-09-12

Tanenholtz, Alvin E.

Textiles: fiber preparation

195115, C12D 1306

Patent

active

041135660

ABSTRACT:
A simple and efficient process for the deacylation of penicillins to 6-aminopenicillanic acid in which an aqueous penicillin solution is rapidly recirculated through a shallow bed comprising particulate immobilized penicillin acylase at 15.degree.-45.degree. C and pH 6.5-9.0 until substantial conversion results.

REFERENCES:
patent: 3239427 (1966-03-01), Huang et al.
patent: 3694314 (1972-09-01), Lloyd et al.
patent: 3910825 (1975-10-01), Huper et al.
patent: 3915797 (1975-10-01), Ishimatsu et al.

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