Process for preparing 6-aminopenicillanic acid

Mineral oils: apparatus – Refining – With filtration

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195 54, 195 29, 195 30, C12D 900

Patent

active

039532917

ABSTRACT:
At least one acryloyl monomer is polymerized in an aqueous suspension containing a penicillin amidase-producing microorganism. The acryloyl monomers employed in the present invention include acryloylamide, N,N'-lower alkylene-bis-acryloylamide, bis(acryloylamidomethyl)ether and N,N'-di-acryloylethyleneurea. The resultant immobilized penicillin amidase-producing microorganism is subjected to enzymatic reaction with penicillin. 6-Amino-penicillanic acid is produced.

REFERENCES:
patent: 3619371 (1971-11-01), Crook et al.
patent: 3736230 (1973-05-01), Delin et al.
patent: 3767790 (1973-10-01), Guttag
patent: 3791926 (1974-02-01), Chibata et al.

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