Process for preparing...

Details Process for preparing... Process for preparing...

2010-06-10

2011-10-18

Balasubramanian, Venkataraman (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

active

08039619

ABSTRACT:
Voriconazole is prepared by a process comprising condensing 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone with 4-chloro-6-ethyl-5-fluoropyrimidine, in a ketone, ether, aliphatic hydrocarbon, or aromatic hydrocarbon solvent, to give (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-diflurophenyl)-1-(1H -1,2,4-triazole-1-yl)butan-2-ol.

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Wikipedia. Hydrogenation [online] [retrieved on Mar. 2, 2011]. Retrieved from the Internet: <http://en.wikipedia.org/wiki/Hydrogenation>, page was last modified on Feb. 28, 2011 at 00:17.

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