Process for preparing 5-fluorocytosine salt

Details Process for preparing 5-fluorocytosine salt Process for preparing 5-fluorocytosine salt

1982-04-14

1984-09-25

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D23947

Patent

active

044736916

ABSTRACT:
5-Fluorocytosine hydrofluoride of high purity is prepared by fluorinating cytosine with fluorine gas in the presence of hydrogen fluoride, followed by treatment of the resultant fluorinated product in the reaction mixture at a temperature higher than the fluorination temperature.

REFERENCES:
patent: 3682917 (1972-08-01), Knuniants et al.
patent: 4029661 (1977-06-01), Schuman et al.
patent: 4122251 (1978-10-01), Misaki et al.

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