Process for preparing 4-substituted imidazole compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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2602937, 544139, 548315, 548336, 548342, C07D23364, C07D23384

Patent

active

041197810

ABSTRACT:
A process for preparing 4-(oxy, thio or amino)methylimidazole compounds via displacement of the trisubstituted phosphonium group from 4-(trisubstituted phosphonium)methylimidazole compounds is disclosed.

REFERENCES:
patent: 3325546 (1967-06-01), Hays
Houben-Weyl, Methoden der Organischen Chemie, vol. XXI, part I, p. 51 (1963).
Zbiral et al., Phosphorus 1972, vol. 2, pp. 29-34.
Berlin et al., Chem. Review 1960, vol. 60, pp. 247-248.
Zbiral, Synthesis 1974, vol. 11, pp. 775-797.
Aksnes et al., Chem. Abst. 1962, vol. 57, cols. 14473-14474.
Allen et al., Chem. Abst. 1974, vol. 80, No. 47138t.
Grayson et al., J. Amer. Chem. Soc. 1959, vol. 81, pp. 4803-4807.
House Modern Synthetic Reactions, pp. 701-702, W. A. Benjamin, 1972.
Organic Reactions, vol. 14, pp. 278-279, N.Y., Wiley, 1965.
Zbiral et al., Tetrahedron Letters 1972, No. 5, pp. 439-444.

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