Process for preparing 4-substituted cis-cyclohexylamines

Details Process for preparing 4-substituted cis-cyclohexylamines Process for preparing 4-substituted cis-cyclohexylamines

1999-03-17

2000-04-04

Barts, Samuel

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564307, C07C20900

Patent

active

060463600

ABSTRACT:
The present invention relates to a process for preparing 4-substituted cis-cyclohexylamines of high cis-selectivity by reductive amination of cyclohexanones which are substituted in position 4 by an organic radical.

REFERENCES:
patent: 3994975 (1976-11-01), Oude Alink et al.
patent: 4954654 (1990-09-01), Efner
patent: 5395972 (1995-03-01), Furutani et al.
Academic Press, 1967, pp. 291-303.
Russian Chemical Reviews, 1980, pp. 14-27.
Nippon Kagaku Kaishi, 1989, pp. 641-647.
J. Chem. Res., 1981, pp. 164-165.

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