Process for preparing 4'-deschlororebeccamycin

Details Process for preparing 4'-deschlororebeccamycin Process for preparing 4'-deschlororebeccamycin

1985-03-18

1986-01-28

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435872, C12P 1718, C12R 1365

Patent

active

045671435

ABSTRACT:
A new antitumor antibiotic designated herein as 4'-deschlororebeccamycin is produced by fermentation of Nocardia aerocolonigenes ATCC 39243. The new compound possesses antibacterial activity and inhibits the growth of tumors in experimental animals.

REFERENCES:
patent: 4524145 (1985-06-01), Matson
J. Antibiotics 30 (4), A New Alkaloid AM-2282 of Steptomyces Origin Taxonomy, Fermentation, Isolation and Preliminary Characterization, S. Omura et. al., pp. 275-282, 1977.
J. C. S. Chem. Comm., X-Ray Crystal Structure of Staurosporing: a New Alkaloid from a Streptomyces Strain, A. Furusaki et. al., pp. 800-801, 1978.
Angew. Chem. Int. Ed. Engl. 19(6), Indole Pigments from the Fruiting Bodies of the Slime Mold Arcyria denudata, W. Steglich et. al., pp. 459-460, 1980.

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