Process for preparing 4-aminomethyl-3-alkoxyiminopyrrolidine...

Details Process for preparing 4-aminomethyl-3-alkoxyiminopyrrolidine... Process for preparing 4-aminomethyl-3-alkoxyiminopyrrolidine...

2007-09-18

2007-09-18

Shameem, Golam M. M. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S541000

Reexamination Certificate

active

10548324

ABSTRACT:
The present invention relates to a process for the preparation of 4-aminomethyl-3-alkoxyiminopyrrolidine methane-sulfonate, a key intermediate of quinolone antibiotics. According to the process of the present invention, the total number of steps has been shortened to 2-3 steps, the solid separation is not required, and the use of costly chemicals, particularly (BOC)2O (t-butoxycarbonyl anhydride), several organic solvents and reactants, is eliminated.

REFERENCES:
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patent: 5869670 (1999-02-01), Hong et al.
patent: 0 688 722 (1999-05-01), None
patent: WO99/07696 (1999-02-01), None
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patent: WO 01/17961 (2001-03-01), None
patent: WO 01/68649 (2001-09-01), None
patent: WO 03/011450 (2003-02-01), None

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