Process for preparing 4(5)-hydroxymethyl 5(4)-lower alkyl imidaz

Details Process for preparing 4(5)-hydroxymethyl 5(4)-lower alkyl imidaz Process for preparing 4(5)-hydroxymethyl 5(4)-lower alkyl imidaz

1979-07-31

1981-06-23

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23364

Patent

active

042752167

ABSTRACT:
Compounds having the formulas ##STR1## in which R is a lower alkyl group, and acid addition salts thereof, are prepared by reacting ##STR2## with formaldehyde, in the presence of a strong base.

REFERENCES:
patent: 4104473 (1978-08-01), Sawa et al.
patent: 4189591 (1980-02-01), Mueller et al.
Godefroi et al., Recueil des Travaux Chimiques des Payslbas, vol. 91, pp. 1383-1392.
Grindley et al., J. Chem. Soc., (London), 1927, pp. 3128-3136.
Hofmann Imidazole and Its Derivatives, Part 1, pp. 99-100, N.Y. Interscience 1953.
Masui et al., Chem. Pharm. Bull., 1974, vol. 22, pp. 2359-2364.

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