Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1978-06-05
1979-09-25
Trousof, Natalie
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546283, 2603475, 2603458R, 549 13, 549 60, 549 88, 549 9, 549 1, C07D40512, C07D30768
Patent
active
041692020
ABSTRACT:
Derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid characterized by having two substituents at position 5 and in addition being optionally further substituted at position 3 with a lower alkyl group, as well as esters therefor are disclosed. The foregoing compounds are useful hypolipidemic agents in a mammal. Novel methods for the preparation of these compounds also are disclosed.
REFERENCES:
patent: 2436532 (1945-02-01), Singleton et al.
Fieser & Fieser, Reagents for Organic Synthesis, John Wiley and Sons, Inc. 1963.
R. E. Rosenkranz et al., Helv. Chim. Acta, 46, 1259 (1963).
G. B. Bennett et al., J. Med. Chem. 18, 709 (1976).
G. N. Khabibulina et al., Chem. Abstr. 85, 159951n (1976).
Cayen Mitchell N.
Dvornik Dushan
Jirkovsky Ivo L.
American Home Products Corporation
Fan Jane T.
Trousof Natalie
Wilfond Arthur E.
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