Process for preparing 4-(4-biphenylyl)-4-oxo-butanoic acid

Details Process for preparing 4-(4-biphenylyl)-4-oxo-butanoic acid Process for preparing 4-(4-biphenylyl)-4-oxo-butanoic acid

1984-11-05

1986-11-04

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 5986

Patent

active

046211543

ABSTRACT:
An improved process for preparing 4-(4-biphenylyl)-4-oxo-butanoic acid which is useful as anti-inflammatory and analgesic agents. The process comprises reacting biphenyl with succinic anhydride in chlorobenzene in the presence of anhydrous aluminum chloride. No 4-(4-chlorophenyl)-4-oxo-butanoic acid is produced as by-product.

REFERENCES:
patent: 3859363 (1975-01-01), Teufel et al.
patent: 3997589 (1976-12-01), Seeger et al.
patent: 4058558 (1977-11-01), Cousse et al.

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