Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1983-08-10
1986-06-24
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435120, 435129, 435130, 435131, 435849, C12P 1716, C12P 1714, C12P 1100, C12R 119
Patent
active
045967776
ABSTRACT:
A compound having the formula ##STR1## can be prepared by enzymatically coupling a compound of the formula ##STR2## with a compound of the formula ##STR3## in the presence of Escherichia coli acylase at a pH of from about 4.0 to about 6.0.
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O'Sullivan et al., "Enzymatic Acylation of Monobactams, The Jour. of Antibiotics, vol. 37, pp. 804-806 (1984).
Aklonis Carol A.
O'Sullivan Joseph
Davis Stephen B.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Weimar Elizabeth C.
Wiseman Thomas G.
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