Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-

Details Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy- Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-

1982-02-01

1984-04-17

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239A, C07D41712, C07D20508, A61K 31425

Patent

active

044433743

ABSTRACT:
Disclosed herein is a process for preparing a compound having the formula ##STR1## which comprises coupling a compound having the formula ##STR2## or a salt thereof, with a compound having the formula ##STR3## to obtain a compound having the formula ##STR4## reacting that compound with 2-aminooxy-2-methylpropanoic acid, or a salt thereof, to obtain a compound having the formula ##STR5## and, if R is an amino protecting group, deprotecting that compound to yield the desired product; wherein

REFERENCES:
patent: 4024133 (1977-05-01), Cook et al.
patent: 4166115 (1979-08-01), Takaya
patent: 4191762 (1980-03-01), Kamiya et al.
patent: 4201779 (1980-05-01), Bormann et al.
patent: 4225707 (1980-09-01), Kamiya et al.
Georgopapadakou et al., European J. Biochem. 124, 507, (1982).

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