Process for preparing...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C546S216000, C546S239000, C546S289000, C546S301000, C546S302000, C546S315000, C546S322000, C546S339000, C560S008000, C560S174000, C562S405000

Reexamination Certificate

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06881845

ABSTRACT:
The present invention relates to a process for preparing (±)-trans-4-p-fluorophenyl-3-hyroxymethyl-1-methylpiperdine of formula (I). The present invention also relates to novel intermediates of the formula (IX) and (IX′) methods for preparing said intermediates and the use of said compounds for preparing Paroxetine and Omiloxetine.

REFERENCES:
patent: 3912743 (1975-10-01), Christensen et al.
patent: 4902801 (1990-02-01), Faruk et al.
patent: 374674 (1990-06-01), None
patent: 0 812 827 (1997-12-01), None
patent: WO 9636636 (1996-11-01), None
patent: WO 9853824 (1998-12-01), None
patent: WO 0026187 (2000-05-01), None
Foguet et al. “Novel process for . . . ” CA 137:78863 (2002).*
RN 103-67-3 CAS registry.*
RN 403-42-9 CAS reistry.*
Pathak et al. “Studies in fluorinated . . . ” CA 94:102967 (1981).*
Stuetz, Anton et al. J. Med. Chem. (1986), 29(1), 112-25.

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