Process for preparing 3-hydroxythiolane

Details Process for preparing 3-hydroxythiolane Process for preparing 3-hydroxythiolane

2007-08-28

2007-08-28

Lambkin, Deborah C. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

11091488

ABSTRACT:
A process for preparing 3-hydroxythiolane which is characterized in reacting a compound of the following formula,wherein X is halogen atom, and R2is substituted or unsubstituted alkyl group, substituted or unsubstituted aralkyl group, or substituted or unsubstituted aryl group, with a metal sulfide.

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H.C. Brown et al., “chiral synthesis via organoboranes. 6. Hydroboration. 74. Asymmetric hydroboration of representative heterocyclic olefins with diiopinocampheylborane. Synthesis of heterocyclic boronates and heterocyclic alcohols of very high enantiomeric purity”, J. Am. Chem. Soc., vol. 108, pp. 2049-2054, 1986.
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