Process for preparing 3-[(benzamidopiperid-1-yl)alkyl] indoles

Details Process for preparing 3-[(benzamidopiperid-1-yl)alkyl] indoles Process for preparing 3-[(benzamidopiperid-1-yl)alkyl] indoles

1977-02-28

1979-07-24

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546197, C07D40106

Patent

active

041622529

ABSTRACT:
The invention provides a new process for preparing indoles in which a 4-acylamido-1-[3-indolyl-alylene] pyridinium compound or a corresponding tetrahydropyridine compound is reduced with alkali metal borohydride in special solvents to give a corresponding piperidine compound.

REFERENCES:
ellzey, S., et al., J. Org. Chem., 32, 846 (1967).
Brown, H., et al., J. Am. Chem. Soc., 77, 6209 (1955).
Yamada, S. et al., Chem. and Ind., pp. 2169-2170 (1966).
Gaylord, N., Reduction with Complex Metal Hydrides, Interscience, New York, 1956, pp. 592-593.

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