Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1977-03-08
1979-02-20
Trousof, Natalie
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546273, C07D40106
Patent
active
041406915
ABSTRACT:
The invention provides a process for preparing indole derivatives in which a compound containing an indole ring linked to an acylamido piperidine ring by a carbonyl alkylene group between the nitrogen of the piperidine and the 3-position of the indole is reduced with alkali-metal borohydride in special solvents so that the carbonyl group is reduced to a CH.sub.2 group.
REFERENCES:
ito, I., et al., Tetrahedron, 30, 1027-1031 (1974).
Brown, H., et al., J. Am. Chem. Soc., 77, 6209 (1955).
Murfitt Susan E.
Weston George O.
John Wyeth & Brother Ltd.
Schwartz Richard A.
Trousof Natalie
Wilfond Arthur E.
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