Process for preparing (2R)-methyl-4,4,4-trifluorobutylamine

Details Process for preparing (2R)-methyl-4,4,4-trifluorobutylamine Process for preparing (2R)-methyl-4,4,4-trifluorobutylamine

1991-12-04

1993-12-28

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

564302, 564303, 564304, 564486, 564488, 564510, 564212, 564366, C07B 5700

Patent

active

052741184

ABSTRACT:
A process for the preparation of (2R)-methyl-4,4,4-trifluorobutylamine, or an acid addition salt thereof which comprises

REFERENCES:
patent: 2243977 (1941-06-01), Peyer
patent: 5105014 (1992-04-01), Neumann
March, Advanced Organic Chemistry, 3rd Ed., (John Wiley & Sons: New York) 1989, pp. 527-529.
Bernstein et al., Chem. Abs. 107: 175881t (1987).
T. Kaneda, "Gas-liquid Chromatographic Separation of Enantiomers as Their Diastereomeric Derivatives, Illustrated with 2-Methylbutyric Acid", Journal of Chromatography (1986), 366, 217-224.

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