Process for preparing 2-oxindole

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20934

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059731656

ABSTRACT:
A process for preparing 2-oxindole includes catalytically reacting isatin with hydrazine hydrate in a polar solvent containing a dissolved weak base at an elevated temperature to form the 2-oxindole product.

REFERENCES:
Crestini et al., A New Efficient and Mild Synthesis of 2-Oxindoles . . . , Synth. Comm., 24(40), 2835-2841, Dec. 1994.

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