Process for preparing 2-amino-4-(haloalkyl) pyridine...

Details Process for preparing 2-amino-4-(haloalkyl) pyridine... Process for preparing 2-amino-4-(haloalkyl) pyridine...

2010-03-11

2011-11-22

Andres, Janet L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

08063226

ABSTRACT:
A process in which a 2-aminopyridine derivative of the general formula II is obtained from open-chain nitrile precursor I or III by reaction with a nitrogen compound in a cyclization reaction is described.

REFERENCES:
patent: 0 228 846 (1992-04-01), None
patent: WO 2007/000249 (2007-01-01), None
Tomcufcik et al., Heterocyclic Chemistry: Pyridine and Its Derivatives, p. III, Chap. 4, Aminopyridines, p. 3 (1961).
Chem. Ber. (1936) 69, Nr. 12. pp. 2593-2605.
Huang, X. et al.,Organic Letters, (2001) vol. 3, No. 21 pp. 3417-3419.
Dunn, A. D. et al.,Journal of Fluorine Chemistry(1999) 93, pp. 153-157.
Mittelbach. et al., “Syntheses with Nitriles, LXXV[1]. The Reactivity of the Dimers of Malononitrile and Cyanoacetate with Dimethylformamide-dimethylacetal”,Monatshefte FürChemie, (1987) 118, pp. 617-626 English Abstract.

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