Process for preparing 2-(3-bromopropyl)-5,5-dimethyl-1,3-dioxane

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549374, C07D31906

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048473910

ABSTRACT:
The invention relates to a process for preparing the ketals of 4-bromobutanal and of 5-bromopentanal of the formula ##STR1## which comprises reacting 2,3-dihydroguran and 3,4-dihydro-2H-pyran respectively in a solvent in the presence of a catalyst with neopentylglycol and then brominating the resulting product. The invention also relates to the said ketal of 5-bromobutanal as such.

REFERENCES:
patent: 4252803 (1981-02-01), Webb
Sandler et al., "Organic Functional Group Preparations", Academic Press, New York, 1968, pp. 116-123.
Forbes, C. et al., J. Chem. Soc., Perkin I (1977), 2353-2355.
Kuehne, M. et al., J. Org. Chem., 46, 2002-2009 (1981).
Little, R. D. et al., J. Org. Chem., 47, 362-364 (1982).
Kulkarni, S. et al., Heterocycles, 18, 163-167 (1982).
Fleming, I. et al., Snyth. Commun., 5, 177-180 (1975).
Meerwein, H., "Preparations of Acetals", in Houben-Weyl, Meth. der Org. Chem., vol. VI(3), (1965), pp. 204-215.
Roedig, A., "Prep. of Bromine Compounds", in Houben-Weyl, Meth. der Org. Chem., vol. V(4) (1960), pp. 361-380.

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