Process for preparing 2,2'-anhydro-1.beta.-D-arabi nofuranosyl-5

Details Process for preparing 2,2'-anhydro-1.beta.-D-arabi nofuranosyl-5 Process for preparing 2,2'-anhydro-1.beta.-D-arabi nofuranosyl-5

1973-01-11

1978-11-07

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 22, C07H 1908

Patent

active

041247574

ABSTRACT:
2,2'-Anhydro-1.beta.-D-arabinofuranosyl-5-fluorocytosine (hereafter AAFC) and its acid addition salts are known compounds. AAFC may now be conveniently prepared in extremely high yield by selective acid catalyzed hydrolysis of the corresponding 3'-O-acyl analogs of AAFC which unexpectedly hydrolyzes at the acyl group while the 2,2'-anhydro linkage remains intact.

REFERENCES:
patent: 3155646 (1964-11-01), Hunter
patent: 3812098 (1974-05-01), Moffatt et al.

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