Process for preparing (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo [1,

Details Process for preparing (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo [1, Process for preparing (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo [1,

1992-06-23

1993-08-31

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540302, C07D48704

Patent

active

052410730

ABSTRACT:
Novel and improved simple process for preparing carbapenem compound, (1R,5S,6S)-2-[(6,7-dihydro-5H-pyrazolo [1,2-a][1,2,4]triazolium-6-yl)]thio-6-[(R)-1-hydroxyethyl]-1-methyl-carbap enem-3-carboxylate represented by the following formula: ##STR1## This compound may be prepared by using a mercapto reagent, 6,7-dihydro-6-mercapto-5H-pyrazolo-[1,2-a][1,2,4]triazolium derivative of the following formula: ##STR2## wherein X.sup..crclbar. is an anion charge.

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