Process for preparing 1-substituted 2-methyl-tetrahydropyrimidin

Details Process for preparing 1-substituted 2-methyl-tetrahydropyrimidin Process for preparing 1-substituted 2-methyl-tetrahydropyrimidin

1975-07-22

1977-01-04

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260561R, 260479S, 260482R, 260561A, 260562N, C07D23906

Patent

active

040012328

ABSTRACT:
1-SUBSTITUTED 2-METHYL-TETRAHYDROPYRIMIDINES ARE PREPARED BY REACTING AN N-substituted propylene diamine with an acetoacetic acid ester or amine at a temperature of from 0.degree. to 80.degree. C and removing the water produced in the reaction at a temperature of from 0.degree. to 80.degree. C.

REFERENCES:
brown; "The Pyrimidines", pp. 445-448 (1962).
Chem. Ber., 98, 3652-3659 (1965).

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