Process for preparing 1,5-benzothiazepine derivatives

Details Process for preparing 1,5-benzothiazepine derivatives Process for preparing 1,5-benzothiazepine derivatives

1991-06-26

1992-07-07

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C07D28102, A61K 3155

Patent

active

051284693

ABSTRACT:
This disclosure describes a process for the preparation of 1,5-benzothiazepinone derivatives. The process involves the use of sulfonic acids as catalysts to effect ring closure to form the 1,5-benzothiazepinone ring. The resulting compounds have well known pharmaceutical properties.

REFERENCES:
patent: 3562257 (1971-02-01), Kugita et al.
patent: 4438035 (1984-03-01), Gaino et al.
patent: 4567175 (1986-01-01), Takeda et al.
patent: 4590188 (1986-05-01), Takeda et al.
patent: 4882326 (1989-11-01), Murakami et al.
patent: 5013835 (1991-05-01), Rossey et al.

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