Process for preparing 1,5-benzothiazepine derivative

Details Process for preparing 1,5-benzothiazepine derivative Process for preparing 1,5-benzothiazepine derivative

1997-02-21

1998-12-08

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C07D28102

Patent

active

058471227

ABSTRACT:
##STR1## wherein Ring A and Ring B are substituted or unsubstituted benzene ring, and R.sup.3 is H, (di-lower alkylamino)-lower alkyl or substituted or unsubstituted piperazinyl-lower alkyl, or a salt thereof, in high yield and in a single step from a novel 3-(2-amino-substituted or unsubstituted phenylthio)-2-hydroxy-3-substituted or unsubstituted phenylpropionamide intermediate for preparing medicaments such as diltiazem hydrochloride.

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