Process for preparing 1,5-benzothiazephine derivatives

Details Process for preparing 1,5-benzothiazephine derivatives Process for preparing 1,5-benzothiazephine derivatives

1982-07-09

1983-11-22

Bond, Robert T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D28102

Patent

active

044168195

ABSTRACT:
A process for preparing 1,5-benzothiazepine derivatives of the formula: ##STR1## wherein Ar is a phenyl substituted with a lower alkoxy, R is a lower alkyl, R.sup.1 and R.sup.2 are each a lower alkyl, and Y is a lower alkylene, which have excellent coronary vasodilating and psychoneurotic activities and are useful particularly as a Ca.sup.++ -antagonistic coronary vasodilator.

REFERENCES:
Kugita et al., "Chem. Pharm. Bull." vol. 18, No. 10, pp. 2028-2037 (1970).
Kugita et al., "Chem. Pharm. Bull." vol. 19, No. 3, pp. 595-602 (1971).

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